ÀÌ»óÈ¿(Sanghyo Lee, Master course)
E-mail : lsh00119@naver.com
Education and Training
- °Ç±¹´ëÇб³ Áٱ⼼Æ÷Àç»ý°øÇаú Á¹¾÷ (ÀÌÇлç, 2024)
- °Ç±¹´ëÇб³ Áٱ⼼Æ÷Àç»ý°øÇÐÀü°ø ¼®»ç°úÁ¤ (2024~)
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Àú´Â ÇãÇ÷¼º ³úÇ÷°ü ÁúȯÀÎ Ä«´Ù½Ç(CADASIL) ȯÀڷκÎÅÍ À¯·¡µÈ ¼¶À¯¾Æ¼¼Æ÷¸¦ reprogrammingÇÏ¿© patient specific iPSCs¸¦ È®¸³ÇÑ ÈÄ, À̸¦ Ç÷°ü°èÅëÀ¸·Î ºÐÈÇÔÀ¸·Î½á ü¿Ü Áúº´ ¸ðµ¨À» Á¦ÀÛÇÑ µÚ Ä«´Ù½Ç ÁúȯÀÇ º´ÀÎ ±Ô¸í ¹× Ä¡·á °¡´É¼ºÀ» ¿¬±¸ ÁßÀÔ´Ï´Ù.
¶ÇÇÑ mitochondrial fission associated genes¸¦ knock outÇÑ mouse embryonic stem cells ¹× neural stem cell ÀÌ¿ëÇÏ¿© ÇØ´ç À¯ÀüÀÚµéÀÌ ¹ÌÅäÄܵ帮¾Æ ºÐ¿ ¹× ¹ÌÅäÆÄÁö¿¡ ¹ÌÄ¡´Â ¿µÇâÀ» ¿¬±¸ÇÏ°í ÀÖ½À´Ï´Ù.
Research interests
1) CADASIL disease modeling
2) Mitochondrial dynamics
3) Neural stem cell